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warfarin definitions

WordNet (r) 3.0 (2005)

n
1: an anticoagulant (trade name Coumadin) use to prevent and treat a thrombus or embolus [syn: warfarin, Coumadin]

Merriam Webster's

noun Etymology: Wisconsin Alumni Research Foundation (its patentee) + coumarin Date: 1950 a crystalline anticoagulant coumarin derivative C19H16O4 used chiefly in the form of its sodium salt as a rodent poison and in medicine

Britannica Concise

Anticoagulant drug, marketed as Coumadin. Originally developed to treat thromboembolism (see thrombosis), it interferes with the liver's metabolism of vitamin K, leading to production of defective coagulation factors. Warfarin therapy risks uncontrollable hemorrhage, either spontaneously or from any cut or bruise; it requires frequent checks to maintain the proper level in the blood. In high concentrations, warfarin is used as a rodent poison, causing death by internal bleeding.

Oxford Reference Dictionary

n. a water-soluble anticoagulant used esp. as a rat poison. Etymology: Wisconsin Alumni Research Foundation + -arin, after COUMARIN



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