Lonesome Lone"some, a. [Compar. Lonesomer; superl. Lonesomest.] 1. Secluded from society; not frequented by human beings; solitary. Like one that on a lonesome road Doth walk in fear and dread. --Coleridge. 2. Conscious of, and somewhat depressed by, solitude; as, to feel lonesome. -- Lone"some*ly, adv. -- Lone"some*ness, n.